Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake

Herbal and dietary supplements are frequently used as weight loss supplements. However, they account for 20% of drug-induced liver injury. Garcinia cambogia's (GC) active compound, hydroxycitric acid, can be found among those supplements. We report a 26-year-old woman who had been taking GC for...

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Autores principales: Ferreira, Victor, Mathieu, Alexandre, Soucy, Geneviève, Giard, Jeanne-Marie, Erard-Poinsot, Domitille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423904/
https://www.ncbi.nlm.nih.gov/pubmed/32821764
http://dx.doi.org/10.14309/crj.0000000000000429
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author Ferreira, Victor
Mathieu, Alexandre
Soucy, Geneviève
Giard, Jeanne-Marie
Erard-Poinsot, Domitille
author_facet Ferreira, Victor
Mathieu, Alexandre
Soucy, Geneviève
Giard, Jeanne-Marie
Erard-Poinsot, Domitille
author_sort Ferreira, Victor
collection PubMed
description Herbal and dietary supplements are frequently used as weight loss supplements. However, they account for 20% of drug-induced liver injury. Garcinia cambogia's (GC) active compound, hydroxycitric acid, can be found among those supplements. We report a 26-year-old woman who had been taking GC for 7 months when she presented with subacute liver failure and ultimately required a liver transplantation. This report highlights the risk of liver injury after long-term use of GC and demonstrates the importance of considering a close and prolonged monitoring of patients in a tertiary liver transplant center.
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spelling pubmed-74239042020-08-19 Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake Ferreira, Victor Mathieu, Alexandre Soucy, Geneviève Giard, Jeanne-Marie Erard-Poinsot, Domitille ACG Case Rep J Case Report Herbal and dietary supplements are frequently used as weight loss supplements. However, they account for 20% of drug-induced liver injury. Garcinia cambogia's (GC) active compound, hydroxycitric acid, can be found among those supplements. We report a 26-year-old woman who had been taking GC for 7 months when she presented with subacute liver failure and ultimately required a liver transplantation. This report highlights the risk of liver injury after long-term use of GC and demonstrates the importance of considering a close and prolonged monitoring of patients in a tertiary liver transplant center. Wolters Kluwer 2020-08-11 /pmc/articles/PMC7423904/ /pubmed/32821764 http://dx.doi.org/10.14309/crj.0000000000000429 Text en © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Ferreira, Victor
Mathieu, Alexandre
Soucy, Geneviève
Giard, Jeanne-Marie
Erard-Poinsot, Domitille
Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake
title Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake
title_full Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake
title_fullStr Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake
title_full_unstemmed Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake
title_short Acute Severe Liver Injury Related to Long-Term Garcinia cambogia Intake
title_sort acute severe liver injury related to long-term garcinia cambogia intake
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423904/
https://www.ncbi.nlm.nih.gov/pubmed/32821764
http://dx.doi.org/10.14309/crj.0000000000000429
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