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Transthyretin interacts with actin regulators in a Drosophila model of familial amyloid polyneuropathy
Familial amyloid polyneuropathy (FAP) is a neurodegenerative disorder whose major hallmark is the deposition of mutated transthyretin (TTR) in the form of amyloid fibrils in the peripheral nervous system (PNS). The exposure of PNS axons to extracellular TTR deposits leads to an axonopathy that culmi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423984/ https://www.ncbi.nlm.nih.gov/pubmed/32788615 http://dx.doi.org/10.1038/s41598-020-70377-4 |