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Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases

Effective treatments for neurodegenerative diseases need to be developed. MiR132 is abundantly expressed in the brain, and it modulates neuron morphology and plays a key role in maintaining neuron survival. Regulating miR132 can effectively improve the symptoms of Alzheimer’s disease. It can also re...

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Detalles Bibliográficos
Autores principales: Su, Yu, Sun, Bixi, Gao, Xiaoshu, Dong, Xinyue, Fu, Lanbo, Zhang, Yingxin, Li, Zhulin, Wang, Yue, Jiang, Hongyu, Han, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424054/
https://www.ncbi.nlm.nih.gov/pubmed/32848773
http://dx.doi.org/10.3389/fphar.2020.01165