Dapagliflozin Promotes Neovascularization by Improving Paracrine Function of Skeletal Muscle Cells in Diabetic Hindlimb Ischemia Mice Through PHD2/HIF-1α Axis

Diabetes mellitus is associated with a high risk of hindlimb ischemia (HLI) progression and an inevitably poor prognosis, including worse limb salvage and mortality. Skeletal muscle cells can secrete angiogenic factors, which could promote neovascularization and blood perfusion recovery. Thus, parac...

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Detalles Bibliográficos
Autores principales: Nugrahaningrum, Dyah Ari, Marcelina, Olivia, Liu, Caiping, Wu, Shourong, Kasim, Vivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424065/
https://www.ncbi.nlm.nih.gov/pubmed/32848736
http://dx.doi.org/10.3389/fphar.2020.01104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424065/
https://www.ncbi.nlm.nih.gov/pubmed/32848736
http://dx.doi.org/10.3389/fphar.2020.01104

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