Straylight due to intraocular lens opacification in a patient with asteroid hyalosis

PURPOSE: To report a rare case of intraocular lens (IOL) calcification in the presence of asteroid hyalosis with in-vivo measurements of straylight before and after treatment. OBSERVATIONS: A patient with asteroid hyalosis presented with complaints of disability glare due to calcifications on the posterior surface of the IOL. Straylight, measured with the C-Quant, was 8.2x elevated compared to normal (log(s) 2.08). Dissolution of the posterior face IOL deposits was performed with a neodymium-doped yttrium aluminum garnet (Nd:YAG) laser, resulting in a significant decrease in straylight (log(s) 1.76), congruent with the patient's subjective improvement. CONCLUSIONS AND IMPORTANCE: To the best of our knowledge, this is the first report describing a patient with an opacified IOL due to asteroid hyalosis with in-vivo measurements of straylight before and after treatment. It illustrates that awareness of glare complaints in patients with an opacified IOL is important, documentation with C-Quant measurements may be helpful in indicating treatment, evaluating the treatment, and following up the patient, and treatment with a Nd:YAG laser may dissolve the opacifications to a clinically satisfactory level.