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Inhibition of Axin1 in osteoblast precursor cells leads to defects in postnatal bone growth through suppressing osteoclast formation

Axin1 is a negative regulator of β-catenin signaling and its role in osteoblast precursor cells remains undefined. In the present studies, we determined changes in postnatal bone growth by deletion of Axin1 in osteoblast precursor cells and analyzed bone growth in newborn and postnatal Axin1(Osx) mi...

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Detalles Bibliográficos
Autores principales: Shu, Bing, Zhao, Yongjian, Zhao, Shitian, Pan, Haobo, Xie, Rong, Yi, Dan, Lu, Ke, Yang, Junjie, Xue, Chunchun, Huang, Jian, Wang, Jing, Zhao, Dongfeng, Xiao, Guozhi, Wang, Yongjun, Chen, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424530/
https://www.ncbi.nlm.nih.gov/pubmed/32821442
http://dx.doi.org/10.1038/s41413-020-0104-5