Cargando…

Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic

OBJECTIVE: To define the aerosol and droplet risks associated with endonasal drilling and to identify mitigation strategies. STUDY DESIGN: Simulation series with fluorescent 3-dimensional (3D) printed sinonasal models and deidentified cadaveric heads. SETTINGS: Dedicated surgical laboratory. SUBJECT...

Descripción completa

Detalles Bibliográficos
Autores principales: Dharmarajan, Harish, Freiser, Monika E., Sim, Edward, Boorgu, Devi Sai Sri Kavya, Corcoran, Timothy E., Wang, Eric W., Gardner, Paul A., Snyderman, Carl H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424614/
https://www.ncbi.nlm.nih.gov/pubmed/32779964
http://dx.doi.org/10.1177/0194599820949802
_version_ 1783570372009918464
author Dharmarajan, Harish
Freiser, Monika E.
Sim, Edward
Boorgu, Devi Sai Sri Kavya
Corcoran, Timothy E.
Wang, Eric W.
Gardner, Paul A.
Snyderman, Carl H.
author_facet Dharmarajan, Harish
Freiser, Monika E.
Sim, Edward
Boorgu, Devi Sai Sri Kavya
Corcoran, Timothy E.
Wang, Eric W.
Gardner, Paul A.
Snyderman, Carl H.
author_sort Dharmarajan, Harish
collection PubMed
description OBJECTIVE: To define the aerosol and droplet risks associated with endonasal drilling and to identify mitigation strategies. STUDY DESIGN: Simulation series with fluorescent 3-dimensional (3D) printed sinonasal models and deidentified cadaveric heads. SETTINGS: Dedicated surgical laboratory. SUBJECTS AND METHODS: Cadaveric specimens irrigated with fluorescent tracer and fluorescent 3D-printed models were drilled. A cascade impactor was used to collect aerosols and small droplets of various aerodynamic diameters under 15 µm. Large droplet generation was measured by evaluating the field for fluorescent debris. Aerosol plumes through the nares were generated via nebulizer, and mitigation measures, including suction and SPIWay devices, nasal sheaths, were evaluated regarding reduction of aerosol escape from the nose. RESULTS: The drilling of cadaveric specimens without flexible suction generated aerosols ≤3.30 µm, and drilling of 3D sinonasal models consistently produced aerosols ≤14.1 µm. Mitigation with SPIWay or diameter-restricted SPIWay produced same results. There was minimal field contamination in the cadaveric models, 0% to 2.77% field tarp area, regardless of drill burr type or drilling location; cutting burr drilling without suction in the 3D model yielded the worst contamination field (36.1%), followed by coarse diamond drilling without suction (19.4%). The simple placement of a flexible suction instrument in the nasal cavity or nasopharynx led to complete elimination of all aerosols ≤14.1 µm, as evaluated by a cascade impactor positioned immediately at the nares. CONCLUSION: Given the findings regarding aerosol risk reduction, we strongly recommend that physicians use a suction instrument in the nasal cavity or nasopharynx during endonasal surgery in the COVID-19 era.
format Online
Article
Text
id pubmed-7424614
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-74246142020-08-13 Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic Dharmarajan, Harish Freiser, Monika E. Sim, Edward Boorgu, Devi Sai Sri Kavya Corcoran, Timothy E. Wang, Eric W. Gardner, Paul A. Snyderman, Carl H. Otolaryngol Head Neck Surg Special Section on COVID-19 OBJECTIVE: To define the aerosol and droplet risks associated with endonasal drilling and to identify mitigation strategies. STUDY DESIGN: Simulation series with fluorescent 3-dimensional (3D) printed sinonasal models and deidentified cadaveric heads. SETTINGS: Dedicated surgical laboratory. SUBJECTS AND METHODS: Cadaveric specimens irrigated with fluorescent tracer and fluorescent 3D-printed models were drilled. A cascade impactor was used to collect aerosols and small droplets of various aerodynamic diameters under 15 µm. Large droplet generation was measured by evaluating the field for fluorescent debris. Aerosol plumes through the nares were generated via nebulizer, and mitigation measures, including suction and SPIWay devices, nasal sheaths, were evaluated regarding reduction of aerosol escape from the nose. RESULTS: The drilling of cadaveric specimens without flexible suction generated aerosols ≤3.30 µm, and drilling of 3D sinonasal models consistently produced aerosols ≤14.1 µm. Mitigation with SPIWay or diameter-restricted SPIWay produced same results. There was minimal field contamination in the cadaveric models, 0% to 2.77% field tarp area, regardless of drill burr type or drilling location; cutting burr drilling without suction in the 3D model yielded the worst contamination field (36.1%), followed by coarse diamond drilling without suction (19.4%). The simple placement of a flexible suction instrument in the nasal cavity or nasopharynx led to complete elimination of all aerosols ≤14.1 µm, as evaluated by a cascade impactor positioned immediately at the nares. CONCLUSION: Given the findings regarding aerosol risk reduction, we strongly recommend that physicians use a suction instrument in the nasal cavity or nasopharynx during endonasal surgery in the COVID-19 era. SAGE Publications 2020-08-11 2021-02 /pmc/articles/PMC7424614/ /pubmed/32779964 http://dx.doi.org/10.1177/0194599820949802 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Special Section on COVID-19
Dharmarajan, Harish
Freiser, Monika E.
Sim, Edward
Boorgu, Devi Sai Sri Kavya
Corcoran, Timothy E.
Wang, Eric W.
Gardner, Paul A.
Snyderman, Carl H.
Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic
title Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic
title_full Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic
title_fullStr Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic
title_full_unstemmed Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic
title_short Droplet and Aerosol Generation With Endonasal Surgery: Methods to Mitigate Risk During the COVID-19 Pandemic
title_sort droplet and aerosol generation with endonasal surgery: methods to mitigate risk during the covid-19 pandemic
topic Special Section on COVID-19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424614/
https://www.ncbi.nlm.nih.gov/pubmed/32779964
http://dx.doi.org/10.1177/0194599820949802
work_keys_str_mv AT dharmarajanharish dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic
AT freisermonikae dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic
AT simedward dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic
AT boorgudevisaisrikavya dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic
AT corcorantimothye dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic
AT wangericw dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic
AT gardnerpaula dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic
AT snydermancarlh dropletandaerosolgenerationwithendonasalsurgerymethodstomitigateriskduringthecovid19pandemic