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Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation
BACKGROUND: This study evaluated the use of comprehensive geriatric assessment (CGA) in older patients undergoing pacemaker implantation. METHODS: In this prospective cohort, CGA was performed in 197 patients ≥75 years at pacemaker implantation and yearly thereafter. CGA embraced the following domai...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424674/ https://www.ncbi.nlm.nih.gov/pubmed/32787787 http://dx.doi.org/10.1186/s12877-020-01685-7 |
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author | Schoenenberger, Andreas W. Russi, Ian Berte, Benjamin Weberndörfer, Vanessa Schoenenberger-Berzins, Renate Chodup, Piotr Beeler, Remo Cuculi, Florim Toggweiler, Stefan Kobza, Richard |
author_facet | Schoenenberger, Andreas W. Russi, Ian Berte, Benjamin Weberndörfer, Vanessa Schoenenberger-Berzins, Renate Chodup, Piotr Beeler, Remo Cuculi, Florim Toggweiler, Stefan Kobza, Richard |
author_sort | Schoenenberger, Andreas W. |
collection | PubMed |
description | BACKGROUND: This study evaluated the use of comprehensive geriatric assessment (CGA) in older patients undergoing pacemaker implantation. METHODS: In this prospective cohort, CGA was performed in 197 patients ≥75 years at pacemaker implantation and yearly thereafter. CGA embraced the following domains: cognition, mobility, nutrition, activities of daily living (ADLs), and falls (with or without loss of consciousness). Based on comorbidities, the Charlson comorbidity index (CCI) was calculated. For predictive analysis, logistic regression was used. RESULTS: During a mean follow-up duration of 2.4 years, the incidence rates of syncope decreased from 0.46 to 0.04 events per year (p < 0.001), and that of falls without loss of consciousness from 0.27 to 0.15 (p < 0.001) before vs. after implantation. Sixty-three patients (32.0%) died. Impaired mobility (OR 2.60, 95%CI 1.22–5.54, p = 0.013), malnutrition (OR 3.26, 95%CI 1.52–7.01, p = 0.002), and a higher CCI (OR per point increase 1.25, 95%CI 1.04–1.50, p = 0.019) at baseline were significant predictors of mortality. Among 169 patients who survived for more than 1 year and thus underwent follow-up CGA, CGA domains did not deteriorate during follow-up, except for ADLs. This decline in ADLs during follow-up was the strongest predictor of later nursing home admission (OR 9.29, 95%CI 1.82–47.49, p = 0.007). Higher baseline age (OR per year increase 1.10, 95%CI 1.02–1.20, p = 0.018) and a higher baseline CCI (OR per point increase 1.32, 95%CI 1.05–1.65, p = 0.017) were associated with a decline in ADLs during follow-up. CONCLUSIONS: CGA is useful to detect functional deficits, which are associated with mortality or nursing home admission after pacemaker implantation. The present study seems to support the use of CGA in older patients undergoing pacemaker implantation as functional deficits and falls are amenable to geriatric interventions. |
format | Online Article Text |
id | pubmed-7424674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-74246742020-08-16 Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation Schoenenberger, Andreas W. Russi, Ian Berte, Benjamin Weberndörfer, Vanessa Schoenenberger-Berzins, Renate Chodup, Piotr Beeler, Remo Cuculi, Florim Toggweiler, Stefan Kobza, Richard BMC Geriatr Research Article BACKGROUND: This study evaluated the use of comprehensive geriatric assessment (CGA) in older patients undergoing pacemaker implantation. METHODS: In this prospective cohort, CGA was performed in 197 patients ≥75 years at pacemaker implantation and yearly thereafter. CGA embraced the following domains: cognition, mobility, nutrition, activities of daily living (ADLs), and falls (with or without loss of consciousness). Based on comorbidities, the Charlson comorbidity index (CCI) was calculated. For predictive analysis, logistic regression was used. RESULTS: During a mean follow-up duration of 2.4 years, the incidence rates of syncope decreased from 0.46 to 0.04 events per year (p < 0.001), and that of falls without loss of consciousness from 0.27 to 0.15 (p < 0.001) before vs. after implantation. Sixty-three patients (32.0%) died. Impaired mobility (OR 2.60, 95%CI 1.22–5.54, p = 0.013), malnutrition (OR 3.26, 95%CI 1.52–7.01, p = 0.002), and a higher CCI (OR per point increase 1.25, 95%CI 1.04–1.50, p = 0.019) at baseline were significant predictors of mortality. Among 169 patients who survived for more than 1 year and thus underwent follow-up CGA, CGA domains did not deteriorate during follow-up, except for ADLs. This decline in ADLs during follow-up was the strongest predictor of later nursing home admission (OR 9.29, 95%CI 1.82–47.49, p = 0.007). Higher baseline age (OR per year increase 1.10, 95%CI 1.02–1.20, p = 0.018) and a higher baseline CCI (OR per point increase 1.32, 95%CI 1.05–1.65, p = 0.017) were associated with a decline in ADLs during follow-up. CONCLUSIONS: CGA is useful to detect functional deficits, which are associated with mortality or nursing home admission after pacemaker implantation. The present study seems to support the use of CGA in older patients undergoing pacemaker implantation as functional deficits and falls are amenable to geriatric interventions. BioMed Central 2020-08-12 /pmc/articles/PMC7424674/ /pubmed/32787787 http://dx.doi.org/10.1186/s12877-020-01685-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Schoenenberger, Andreas W. Russi, Ian Berte, Benjamin Weberndörfer, Vanessa Schoenenberger-Berzins, Renate Chodup, Piotr Beeler, Remo Cuculi, Florim Toggweiler, Stefan Kobza, Richard Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation |
title | Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation |
title_full | Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation |
title_fullStr | Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation |
title_full_unstemmed | Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation |
title_short | Evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation |
title_sort | evaluation of comprehensive geriatric assessment in older patients undergoing pacemaker implantation |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424674/ https://www.ncbi.nlm.nih.gov/pubmed/32787787 http://dx.doi.org/10.1186/s12877-020-01685-7 |
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