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Honokiol-Chlorambucil Co-Prodrugs Selectively Enhance the Killing Effect through STAT3 Binding on Lymphocytic Leukemia Cells In Vitro and In Vivo

[Image: see text] The broad-spectrum DNA alkylating therapeutic, chlorambucil (CBL), has limited safety and shows lower therapy effect because of a short half-life while used in the clinic. Therefore, it is very necessary to develop a more efficient and safer type of CBL derivate against tumors with...

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Detalles Bibliográficos
Autores principales:	Xia, Li, Kang, Dali, Wan, Dan, Chu, Chu, Chen, Meizi, Zhang, Shuihan, Li, Xiong, He, Leye, Yan, Jianye, Liu, Teng, Peng, Yongbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424726/ https://www.ncbi.nlm.nih.gov/pubmed/32803080 http://dx.doi.org/10.1021/acsomega.0c02832

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