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The mitochondrial transcription machinery genes are upregulated in acute myeloid leukemia and associated with poor clinical outcome

BACKGROUND: Acute myeloid leukemia (AML) is characterized by rapid growth of abnormal blasts that overcrowd normal hematopoiesis. Defective mitochondrial biogenesis has been implicated in AML, which we believe is partly due to the deregulation of the mitochondrial transcription machinery (MTM) genes...

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Detalles Bibliográficos
Autores principales:	Wu, Sharon, Fahmy, Nicole, Alachkar, Houda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424792/ https://www.ncbi.nlm.nih.gov/pubmed/32812906 http://dx.doi.org/10.1016/j.metop.2019.100009

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