The mitochondrial K-ATP channel opener diazoxide upregulates STIM1 and Orai1 via ROS and the MAPK pathway in adult rat cardiomyocytes

BACKGROUND: Openers of mitochondrial adenosine triphosphate-dependent potassium (mKATP) channels like diazoxide increase reactive oxygen species (ROS) production in cardiac cells and reduce Ca(2+) elevations produced by ischemia–reperfusion, protecting the heart from damage. In this study we tested...

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Detalles Bibliográficos
Autores principales: Gavali, Joice T., Carrillo, Elba D., García, María C., Sánchez, Jorge A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424994/
https://www.ncbi.nlm.nih.gov/pubmed/32817784
http://dx.doi.org/10.1186/s13578-020-00460-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424994/
https://www.ncbi.nlm.nih.gov/pubmed/32817784
http://dx.doi.org/10.1186/s13578-020-00460-w

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