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Aducanumab, gantenerumab, BAN2401, and ALZ-801—the first wave of amyloid-targeting drugs for Alzheimer’s disease with potential for near term approval

The body of evidence suggesting a causative, initiating role of beta amyloid (Aβ) in the pathogenesis of Alzheimer’s disease (AD) is substantial. Yet, only a few anti-amyloid agents have shown meaningful efficacy in clinical trials. We evaluated the unifying characteristics of anti-amyloid agents wi...

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Detalles Bibliográficos
Autores principales:	Tolar, Martin, Abushakra, Susan, Hey, John A., Porsteinsson, Anton, Sabbagh, Marwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424995/ https://www.ncbi.nlm.nih.gov/pubmed/32787971 http://dx.doi.org/10.1186/s13195-020-00663-w

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