Cargando…

Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

BACKGROUND: Mesenchymal stem cell (MSC)-derived exosomes emerge as promising candidates for treating delayed wound healing in diabetes due to the promotion of angiogenesis. Preconditioned MSC with chemical or biological factors could possibly enhance the biological activities of MSC-derived exosomes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Muyu, Liu, Wei, Li, Junxian, Lu, Junxi, Lu, Huijuan, Jia, Weiping, Liu, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425015/ https://www.ncbi.nlm.nih.gov/pubmed/32787917 http://dx.doi.org/10.1186/s13287-020-01824-2

Ejemplares similares

Computer Simulation of TSP1 Inhibition of VEGF–Akt–eNOS: An Angiogenesis Triple Threat
por: Bazzazi, Hojjat, et al.
Publicado: (2018)

Marine Compound Catunaregin Inhibits Angiogenesis through the Modulation of Phosphorylation of Akt and eNOS in vivo and in vitro
por: Liu, Jun-Xiu, et al.
Publicado: (2014)

Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway
por: Zhou, Caixia, et al.
Publicado: (2022)

Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN/AKT pathway
por: Liu, Wei, et al.
Publicado: (2020)

Thyrotropin Regulates eNOS Expression in the Endothelium by PGRN Through Akt Pathway
por: Jiang, Fengwei, et al.
Publicado: (2018)

Acarbose Accelerates Wound Healing via Akt/eNOS Signaling in db/db Mice
por: Han, Xue, et al.
Publicado: (2017)

Molecular mechanisms underlying pharmacological stimulation of eNOS expression and eNOS activity
por: Li, Huige, et al.
Publicado: (2009)

Radix Astragalus Polysaccharide Accelerates Angiogenesis by Activating AKT/eNOS to Promote Nerve Regeneration and Functional Recovery
por: Zhang, Geyi, et al.
Publicado: (2022)

Crocetin promotes angiogenesis in human endothelial cells through PI3K-Akt-eNOS signaling pathway
por: Nasirzadeh, Mahdieh, et al.
Publicado: (2019)

Ursolic acid prevents doxorubicin‐induced cardiac toxicity in mice through eNOS activation and inhibition of eNOS uncoupling
por: Mu, Haiman, et al.
Publicado: (2019)

Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice
por: Zhang, Hong, et al.
Publicado: (2022)

Atorvastatin at Reperfusion Reduces Myocardial Infarct Size in Mice by Activating eNOS in Bone Marrow-Derived Cells
por: Tian, Yikui, et al.
Publicado: (2014)

ADAMTS-1 inhibits angiogenesis via the PI3K/Akt-eNOS-VEGF pathway in lung cancer cells
por: Wang, Bu, et al.
Publicado: (2019)

The proliferation and angiogenesis in hemangioma-derived endothelial cells is affected by STC2 medicated VEGFR2/Akt/eNOS pathway
por: Ren, Shanshan, et al.
Publicado: (2023)

Rosuvastatin Enhances Angiogenesis via eNOS-Dependent Mobilization of Endothelial Progenitor Cells
por: Zhou, Junlan, et al.
Publicado: (2013)

Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway
por: Li, Bo, et al.
Publicado: (2020)

Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways
por: Lu, Xi-Lin, et al.
Publicado: (2012)

Andrographolide Protects against HG-Induced Inflammation, Apoptosis, Migration, and Impairment of Angiogenesis via PI3K/AKT-eNOS Signalling in HUVECs
por: Duan, Ming-Xia, et al.
Publicado: (2019)

Total flavonoids from Astragalus alleviate endothelial dysfunction by activating the Akt/eNOS pathway
por: Liu, Qian, et al.
Publicado: (2017)

GPR87 Promotes Metastasis through the AKT-eNOS-NO Axis in Lung Adenocarcinoma
por: Ahn, Hye-Mi, et al.
Publicado: (2021)

Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis
por: Boopathy, Gandhi T. K., et al.
Publicado: (2017)

Effects of Simulated Microgravity on Human Umbilical Vein Endothelial Cell Angiogenesis and Role of the PI3K-Akt-eNOS Signal Pathway
por: Shi, Fei, et al.
Publicado: (2012)

Matrine attenuates high‐fat diet‐induced in vivo and ox‐LDL‐induced in vitro vascular injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways
por: Zhang, Song, et al.
Publicado: (2019)

κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway
por: Cui, Yan, et al.
Publicado: (2019)

Bioengineered MSC-derived exosomes in skin wound repair and regeneration
por: Zhao, Hanxing, et al.
Publicado: (2023)

Heterozygous eNOS Deficient Mice as a Model to Examine the Effects of eNOS Haploinsufficiency on the Cerebral Circulation
por: Didion, Sean P.
Publicado: (2017)

mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling
por: Wang, Yiying, et al.
Publicado: (2022)

Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway
por: Dou, Jianxin, et al.
Publicado: (2014)

Cryptotanshinone exhibits therapeutical effects on cerebral stroke through the PI3K/AKT-eNOS signaling pathway
por: Zhu, Weixin, et al.
Publicado: (2017)

Paternal eNOS deficiency in mice affects glucose homeostasis and liver glycogen in male offspring without inheritance of eNOS deficiency itself
por: Hocher, Berthold, et al.
Publicado: (2022)

Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis
por: Hu, Yiqiang, et al.
Publicado: (2021)

Yangjing Capsule Can Improve the Function of the Testicular Angiogenesis through Activating VEGFA/eNOS Signaling Pathway
por: Jin, Baofang, et al.
Publicado: (2020)

Pretreatment with β-Boswellic Acid Improves Blood Stasis Induced Endothelial Dysfunction: Role of eNOS Activation
por: Wang, Mingming, et al.
Publicado: (2015)

Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling
por: Wang, Jianhua, et al.
Publicado: (2023)

Assessment of the effect of diode laser therapy on incisional wound healing and expression of iNOS and eNOS on rat oral tissue
por: Ghalayani, Parichehr, et al.
Publicado: (2013)

Metabolic syndrome in rats is associated with erectile dysfunction by impairing PI3K/Akt/eNOS activity
por: Li, Rui, et al.
Publicado: (2017)

Mild Mitochondrial Uncoupling and Calorie Restriction Increase Fasting eNOS, Akt and Mitochondrial Biogenesis
por: Cerqueira, Fernanda M., et al.
Publicado: (2011)

Nafamostat mesilate promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway
por: Choi, Sujeong, et al.
Publicado: (2016)

Hydrogen sulfide donor activates AKT-eNOS signaling and promotes lymphatic vessel formation
por: Aithabathula, Ravi Varma, et al.
Publicado: (2023)

Association of genetic polymorphisms of eNOS with glaucoma
por: Liao, Qiong, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_lvn4f8uokvji6n2vi8d1450c93