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Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer’s disease

BACKGROUND: The amyloid precursor protein (APP) is a transmembrane glycoprotein that undergoes alternative proteolytic processing. Its processing through the amyloidogenic pathway originates a large sAPPβ ectodomain fragment and the β-amyloid peptide, while non-amyloidogenic processing generates sAP...

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Detalles Bibliográficos
Autores principales:	Boix, Claudia P., Lopez-Font, Inmaculada, Cuchillo-Ibañez, Inmaculada, Sáez-Valero, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425076/ https://www.ncbi.nlm.nih.gov/pubmed/32787955 http://dx.doi.org/10.1186/s13195-020-00664-9

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