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Therapeutic implications of the anergic/postactivated status of B cells in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is characterised by numerous abnormalities in B lineage cells, including increased CD27++ plasmablasts/plasma cells, atypical CD27-IgD- B cells with increased CD95, spleen tyrosine kinase (Syk)++, CXCR5- and CXCR5+ subsets and anergic CD11c+Tbet+ age-associated B c...

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Detalles Bibliográficos
Autores principales:	Dörner, Thomas, Szelinski, Franziska, Lino, Andreia C, Lipsky, Peter E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Lupus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425190/ https://www.ncbi.nlm.nih.gov/pubmed/32675278 http://dx.doi.org/10.1136/rmdopen-2020-001258

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