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Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report

Nasal chondromesenchymal hamartoma (NCMH) is a rare destructive benign neoplasm that predominantly develops in infants and young children. The lesion is usually located in the nasal cavity, often in the adjacent paranasal sinuses and orbital region and especially in the ethmoid sinus. Because the im...

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Autores principales: Cui, Ya-qiong, Wang, Li-li, Huang, Gang, Zhao, Lian-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425268/
https://www.ncbi.nlm.nih.gov/pubmed/32780662
http://dx.doi.org/10.1177/0300060520920431
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author Cui, Ya-qiong
Wang, Li-li
Huang, Gang
Zhao, Lian-ping
author_facet Cui, Ya-qiong
Wang, Li-li
Huang, Gang
Zhao, Lian-ping
author_sort Cui, Ya-qiong
collection PubMed
description Nasal chondromesenchymal hamartoma (NCMH) is a rare destructive benign neoplasm that predominantly develops in infants and young children. The lesion is usually located in the nasal cavity, often in the adjacent paranasal sinuses and orbital region and especially in the ethmoid sinus. Because the imaging characteristics of NCMH often mimic the features of malignant tumors, it is clinically important to study the radiographic appearance of this disease. Therefore, we herein present the computed tomography and magnetic resonance imaging findings of NCMH occurring in a 7-year-old girl. The mass was resected via an endoscopic surgical approach and definitively diagnosed as NCMH based on histologic and immunohistochemical analysis. However, signs of tumor recurrence manifested 45 months after surgery. NCMH can be locally aggressive with an expansive and destructive radiographic appearance, which highly implies a malignant neoplasm. Hence, an accurate diagnosis is essential to avoid potentially harmful therapies, and detailed computed tomography or magnetic resonance imaging should be performed prior to surgery. Selective arterial embolization is also an important part of preoperative management because the degree of enhancement may not be adequate to determine the blood supply of the tumor. Moreover, complete radical excision cannot guarantee that the lesion will not recur.
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spelling pubmed-74252682020-08-25 Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report Cui, Ya-qiong Wang, Li-li Huang, Gang Zhao, Lian-ping J Int Med Res Case Report Nasal chondromesenchymal hamartoma (NCMH) is a rare destructive benign neoplasm that predominantly develops in infants and young children. The lesion is usually located in the nasal cavity, often in the adjacent paranasal sinuses and orbital region and especially in the ethmoid sinus. Because the imaging characteristics of NCMH often mimic the features of malignant tumors, it is clinically important to study the radiographic appearance of this disease. Therefore, we herein present the computed tomography and magnetic resonance imaging findings of NCMH occurring in a 7-year-old girl. The mass was resected via an endoscopic surgical approach and definitively diagnosed as NCMH based on histologic and immunohistochemical analysis. However, signs of tumor recurrence manifested 45 months after surgery. NCMH can be locally aggressive with an expansive and destructive radiographic appearance, which highly implies a malignant neoplasm. Hence, an accurate diagnosis is essential to avoid potentially harmful therapies, and detailed computed tomography or magnetic resonance imaging should be performed prior to surgery. Selective arterial embolization is also an important part of preoperative management because the degree of enhancement may not be adequate to determine the blood supply of the tumor. Moreover, complete radical excision cannot guarantee that the lesion will not recur. SAGE Publications 2020-08-11 /pmc/articles/PMC7425268/ /pubmed/32780662 http://dx.doi.org/10.1177/0300060520920431 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Cui, Ya-qiong
Wang, Li-li
Huang, Gang
Zhao, Lian-ping
Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report
title Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report
title_full Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report
title_fullStr Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report
title_full_unstemmed Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report
title_short Computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report
title_sort computed tomography and magnetic resonance imaging findings of nasal chondromesenchymal hamartoma in a young child: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425268/
https://www.ncbi.nlm.nih.gov/pubmed/32780662
http://dx.doi.org/10.1177/0300060520920431
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