Cargando…

Solitary plasmacytoma of the occipital bone: a case report

Solitary plasmacytoma (SP) of the skull is an uncommon clinical entity that is characterized by a localized proliferation of neoplastic monoclonal plasma cells. This case report describes a 50-year-old male that presented with a headache and an exophytic soft mass on the occiput. The diagnosis of SP...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lei, Ren, Nian-Jun, Cai, Hao, Cheng, Hao-Feng, Zhang, Hai-Lin, Peng, Xu-Bin, He, Zheng-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425286/
https://www.ncbi.nlm.nih.gov/pubmed/32780654
http://dx.doi.org/10.1177/0300060520914817
_version_ 1783570469023121408
author Wang, Lei
Ren, Nian-Jun
Cai, Hao
Cheng, Hao-Feng
Zhang, Hai-Lin
Peng, Xu-Bin
He, Zheng-Wen
author_facet Wang, Lei
Ren, Nian-Jun
Cai, Hao
Cheng, Hao-Feng
Zhang, Hai-Lin
Peng, Xu-Bin
He, Zheng-Wen
author_sort Wang, Lei
collection PubMed
description Solitary plasmacytoma (SP) of the skull is an uncommon clinical entity that is characterized by a localized proliferation of neoplastic monoclonal plasma cells. This case report describes a 50-year-old male that presented with a headache and an exophytic soft mass on the occiput. The diagnosis of SP was based on the pathological results and imaging examinations. The patient underwent occipital craniotomy, skull reconstruction and lower trapezius myocutaneous flap (LTMF) transplantation under general anaesthesia. The tumour was capsulized and extended to the subcutaneous and the subdural space through the dura mater with skull defects. The neoplasm of the occipital bone involved large areas of scalp and subcutaneous tissue, which resulted in a large postoperative scalp defect that was repaired using LTMF transplantation. All of the tumour was removed and the transplanted flap grew well. Follow-up at 5 months identified an aggressive mass lesion on the right frontal lobe. The patient received six cycles of the PAD chemotherapy regimen (bortezomib, doxorubicin and dexamethasone) and the lesion was significantly reduced. This case demonstrates that LTMF is an alternative approach for the repair of scalp and subcutaneous soft tissue defects caused by the excision of a large malignant tumour of the occipital region. Chemotherapy is the choice of treatment for neoplastic recurrence.
format Online
Article
Text
id pubmed-7425286
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-74252862020-08-25 Solitary plasmacytoma of the occipital bone: a case report Wang, Lei Ren, Nian-Jun Cai, Hao Cheng, Hao-Feng Zhang, Hai-Lin Peng, Xu-Bin He, Zheng-Wen J Int Med Res Case Report Solitary plasmacytoma (SP) of the skull is an uncommon clinical entity that is characterized by a localized proliferation of neoplastic monoclonal plasma cells. This case report describes a 50-year-old male that presented with a headache and an exophytic soft mass on the occiput. The diagnosis of SP was based on the pathological results and imaging examinations. The patient underwent occipital craniotomy, skull reconstruction and lower trapezius myocutaneous flap (LTMF) transplantation under general anaesthesia. The tumour was capsulized and extended to the subcutaneous and the subdural space through the dura mater with skull defects. The neoplasm of the occipital bone involved large areas of scalp and subcutaneous tissue, which resulted in a large postoperative scalp defect that was repaired using LTMF transplantation. All of the tumour was removed and the transplanted flap grew well. Follow-up at 5 months identified an aggressive mass lesion on the right frontal lobe. The patient received six cycles of the PAD chemotherapy regimen (bortezomib, doxorubicin and dexamethasone) and the lesion was significantly reduced. This case demonstrates that LTMF is an alternative approach for the repair of scalp and subcutaneous soft tissue defects caused by the excision of a large malignant tumour of the occipital region. Chemotherapy is the choice of treatment for neoplastic recurrence. SAGE Publications 2020-08-11 /pmc/articles/PMC7425286/ /pubmed/32780654 http://dx.doi.org/10.1177/0300060520914817 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Wang, Lei
Ren, Nian-Jun
Cai, Hao
Cheng, Hao-Feng
Zhang, Hai-Lin
Peng, Xu-Bin
He, Zheng-Wen
Solitary plasmacytoma of the occipital bone: a case report
title Solitary plasmacytoma of the occipital bone: a case report
title_full Solitary plasmacytoma of the occipital bone: a case report
title_fullStr Solitary plasmacytoma of the occipital bone: a case report
title_full_unstemmed Solitary plasmacytoma of the occipital bone: a case report
title_short Solitary plasmacytoma of the occipital bone: a case report
title_sort solitary plasmacytoma of the occipital bone: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425286/
https://www.ncbi.nlm.nih.gov/pubmed/32780654
http://dx.doi.org/10.1177/0300060520914817
work_keys_str_mv AT wanglei solitaryplasmacytomaoftheoccipitalboneacasereport
AT rennianjun solitaryplasmacytomaoftheoccipitalboneacasereport
AT caihao solitaryplasmacytomaoftheoccipitalboneacasereport
AT chenghaofeng solitaryplasmacytomaoftheoccipitalboneacasereport
AT zhanghailin solitaryplasmacytomaoftheoccipitalboneacasereport
AT pengxubin solitaryplasmacytomaoftheoccipitalboneacasereport
AT hezhengwen solitaryplasmacytomaoftheoccipitalboneacasereport