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Solitary plasmacytoma of the occipital bone: a case report
Solitary plasmacytoma (SP) of the skull is an uncommon clinical entity that is characterized by a localized proliferation of neoplastic monoclonal plasma cells. This case report describes a 50-year-old male that presented with a headache and an exophytic soft mass on the occiput. The diagnosis of SP...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425286/ https://www.ncbi.nlm.nih.gov/pubmed/32780654 http://dx.doi.org/10.1177/0300060520914817 |
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author | Wang, Lei Ren, Nian-Jun Cai, Hao Cheng, Hao-Feng Zhang, Hai-Lin Peng, Xu-Bin He, Zheng-Wen |
author_facet | Wang, Lei Ren, Nian-Jun Cai, Hao Cheng, Hao-Feng Zhang, Hai-Lin Peng, Xu-Bin He, Zheng-Wen |
author_sort | Wang, Lei |
collection | PubMed |
description | Solitary plasmacytoma (SP) of the skull is an uncommon clinical entity that is characterized by a localized proliferation of neoplastic monoclonal plasma cells. This case report describes a 50-year-old male that presented with a headache and an exophytic soft mass on the occiput. The diagnosis of SP was based on the pathological results and imaging examinations. The patient underwent occipital craniotomy, skull reconstruction and lower trapezius myocutaneous flap (LTMF) transplantation under general anaesthesia. The tumour was capsulized and extended to the subcutaneous and the subdural space through the dura mater with skull defects. The neoplasm of the occipital bone involved large areas of scalp and subcutaneous tissue, which resulted in a large postoperative scalp defect that was repaired using LTMF transplantation. All of the tumour was removed and the transplanted flap grew well. Follow-up at 5 months identified an aggressive mass lesion on the right frontal lobe. The patient received six cycles of the PAD chemotherapy regimen (bortezomib, doxorubicin and dexamethasone) and the lesion was significantly reduced. This case demonstrates that LTMF is an alternative approach for the repair of scalp and subcutaneous soft tissue defects caused by the excision of a large malignant tumour of the occipital region. Chemotherapy is the choice of treatment for neoplastic recurrence. |
format | Online Article Text |
id | pubmed-7425286 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-74252862020-08-25 Solitary plasmacytoma of the occipital bone: a case report Wang, Lei Ren, Nian-Jun Cai, Hao Cheng, Hao-Feng Zhang, Hai-Lin Peng, Xu-Bin He, Zheng-Wen J Int Med Res Case Report Solitary plasmacytoma (SP) of the skull is an uncommon clinical entity that is characterized by a localized proliferation of neoplastic monoclonal plasma cells. This case report describes a 50-year-old male that presented with a headache and an exophytic soft mass on the occiput. The diagnosis of SP was based on the pathological results and imaging examinations. The patient underwent occipital craniotomy, skull reconstruction and lower trapezius myocutaneous flap (LTMF) transplantation under general anaesthesia. The tumour was capsulized and extended to the subcutaneous and the subdural space through the dura mater with skull defects. The neoplasm of the occipital bone involved large areas of scalp and subcutaneous tissue, which resulted in a large postoperative scalp defect that was repaired using LTMF transplantation. All of the tumour was removed and the transplanted flap grew well. Follow-up at 5 months identified an aggressive mass lesion on the right frontal lobe. The patient received six cycles of the PAD chemotherapy regimen (bortezomib, doxorubicin and dexamethasone) and the lesion was significantly reduced. This case demonstrates that LTMF is an alternative approach for the repair of scalp and subcutaneous soft tissue defects caused by the excision of a large malignant tumour of the occipital region. Chemotherapy is the choice of treatment for neoplastic recurrence. SAGE Publications 2020-08-11 /pmc/articles/PMC7425286/ /pubmed/32780654 http://dx.doi.org/10.1177/0300060520914817 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Wang, Lei Ren, Nian-Jun Cai, Hao Cheng, Hao-Feng Zhang, Hai-Lin Peng, Xu-Bin He, Zheng-Wen Solitary plasmacytoma of the occipital bone: a case report |
title | Solitary plasmacytoma of the occipital bone: a case report |
title_full | Solitary plasmacytoma of the occipital bone: a case report |
title_fullStr | Solitary plasmacytoma of the occipital bone: a case report |
title_full_unstemmed | Solitary plasmacytoma of the occipital bone: a case report |
title_short | Solitary plasmacytoma of the occipital bone: a case report |
title_sort | solitary plasmacytoma of the occipital bone: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425286/ https://www.ncbi.nlm.nih.gov/pubmed/32780654 http://dx.doi.org/10.1177/0300060520914817 |
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