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miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling

Whether serine protease inhibitor Kazal type 1 (SPINK1) being associated with enzalutamide (Enz) resistance and metastasis of castration-resistant prostate cancer (CRPC) has not been clear. SPINK1 promoted Enz resistance by upregulating Androgen receptor splicing variant 7 (ARv7), and enhanced the i...

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Detalles Bibliográficos
Autores principales:	Wang, Zhi-Chao, Li, Yan, Wang, Ke-Liang, Wang, Lu, You, Bo-Sen, Zhao, Dan-Feng, Liu, Zhong-Qing, Fang, Rui-Zhe, Wang, Jia-Qi, Zhang, Wei, Zhang, Jin-Ming, Xu, Wan-Hai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425449/ https://www.ncbi.nlm.nih.gov/pubmed/32694237 http://dx.doi.org/10.18632/aging.103485

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