Evaluation of the role of B7-H3 haplotype in association with impaired B7-H3 expression and protection against type 1 diabetes in Chinese Han population

BACKGROUND: Type 1 Diabetes (T1D) is a T cell-mediated autoimmune disorder caused by the destruction of insulin-secreting cells. B7-H3 (CD276) plays a vital role in T cell response. However, B7-H3 expression and its clinical significance in T1D remain unclear. The aim of this study was to investigat...

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Detalles Bibliográficos
Autores principales: Ding, Sisi, Shan, Yimei, Sun, Lili, Li, Sicheng, Jiang, Rong, Chang, Xin, Huang, Ziyi, Sun, Jing, Liu, Cuiping, Fang, Chen, Zhang, Xueguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425597/
https://www.ncbi.nlm.nih.gov/pubmed/32787907
http://dx.doi.org/10.1186/s12902-020-00592-7

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