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Hirudin Protects Against Kidney Damage in Streptozotocin-Induced Diabetic Nephropathy Rats by Inhibiting Inflammation via P38 MAPK/NF-κB Pathway

BACKGROUND: Inflammation-induced podocyte apoptosis plays an important role in kidney injury during diabetic nephropathy (DN). Hirudin (HIR), a natural compound extracted from leeches, can inhibit inflammation. However, whether HIR can protect the kidneys against inflammation during DN is unknown. I...

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Detalles Bibliográficos
Autores principales:	Han, Jiarui, Pang, Xinxin, Zhang, Yage, Peng, Zining, Shi, Xiujie, Xing, Yufeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425656/ https://www.ncbi.nlm.nih.gov/pubmed/32848363 http://dx.doi.org/10.2147/DDDT.S257613

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