Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model

To improve the efficacy of nucleic acid-based therapeutics, e.g., small interfering RNA (siRNA), transfection agents are needed for efficient delivery into cells. Several classes of dendrimers have been found useful as transfection agents for the delivery of siRNA because their surface can readily b...

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Detalles Bibliográficos
Autores principales: Bohr, Adam, Tsapis, Nicolas, Foged, Camilla, Andreana, Ilaria, Yang, Mingshi, Fattal, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425770/
https://www.ncbi.nlm.nih.gov/pubmed/32798665
http://dx.doi.org/10.1016/j.ejpb.2020.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425770/
https://www.ncbi.nlm.nih.gov/pubmed/32798665
http://dx.doi.org/10.1016/j.ejpb.2020.08.009

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