Identification of peptides interfering with the LRRK2/PP1 interaction

Serine/threonine phosphatases are responsible for modulating the activities of the protein kinases implicated in the development of several pathologies. Here we identified by a PEP-scan approach a peptide of LRRK2, a Parkinson’s disease associated protein, interacting with the phosphatase PP1. In or...

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Detalles Bibliográficos
Autores principales: Dong, Chang Zhi, Bruzzoni-Giovanelli, Heriberto, Yu, Yanhua, Dorgham, Karim, Parizot, Christophe, Zini, Jean Marc, Brossas, Jean Yves, Tuffery, Pierre, Rebollo, Angelita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425875/
https://www.ncbi.nlm.nih.gov/pubmed/32790695
http://dx.doi.org/10.1371/journal.pone.0237110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425875/
https://www.ncbi.nlm.nih.gov/pubmed/32790695
http://dx.doi.org/10.1371/journal.pone.0237110

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