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Identification of peptides interfering with the LRRK2/PP1 interaction
Serine/threonine phosphatases are responsible for modulating the activities of the protein kinases implicated in the development of several pathologies. Here we identified by a PEP-scan approach a peptide of LRRK2, a Parkinson’s disease associated protein, interacting with the phosphatase PP1. In or...
Autores principales: | Dong, Chang Zhi, Bruzzoni-Giovanelli, Heriberto, Yu, Yanhua, Dorgham, Karim, Parizot, Christophe, Zini, Jean Marc, Brossas, Jean Yves, Tuffery, Pierre, Rebollo, Angelita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425875/ https://www.ncbi.nlm.nih.gov/pubmed/32790695 http://dx.doi.org/10.1371/journal.pone.0237110 |
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