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Targeting steroid receptor RNA activator (SRA), a long non-coding RNA, enhances melanogenesis through activation of TRP1 and inhibition of p38 phosphorylation

Abnormal skin melanin homeostasis results in refractory pigmentary diseases. Melanogenesis is influenced by gene regulation, ultraviolet radiation, and host epigenetic responses. Steroid receptor RNA activator (SRA), a long noncoding RNA, is known to regulate steroidogenesis and tumorigenesis. Howev...

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Detalles Bibliográficos
Autores principales: Ho, Ji-Chen, Lee, Chih-Hung, Hong, Chien-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425936/
https://www.ncbi.nlm.nih.gov/pubmed/32790741
http://dx.doi.org/10.1371/journal.pone.0237577

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