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Development of a Counterselectable Transposon To Create Markerless Knockouts from an 18,432-Clone Ordered Mycobacterium bovis Bacillus Calmette-Guérin Mutant Resource

Mutant resources are essential to improve our understanding of the biology of slow-growing mycobacteria, which include the causative agents of tuberculosis in various species, including humans. The generation of deletion mutants in slow-growing mycobacteria in a gene-by-gene approach in order to mak...

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Detalles Bibliográficos
Autores principales: Borgers, Katlyn, Vandewalle, Kristof, Van Hecke, Annelies, Michielsen, Gitte, Plets, Evelyn, van Schie, Loes, Vanmarcke, Sandrine, Schindfessel, Laurent, Festjens, Nele, Callewaert, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426150/
https://www.ncbi.nlm.nih.gov/pubmed/32788404
http://dx.doi.org/10.1128/mSystems.00180-20