Combining Clinical and Candidate Gene Data into a Risk Score for Azathioprine-Associated Leukopenia in Routine Clinical Practice

Leukopenia is a serious, frequent side effect associated with azathioprine use. Currently, we use thiopurine methyltransferase (TPMT) testing to predict leukopenia in patients taking azathioprine. We hypothesized that a risk score incorporating additional clinical and genetic variables would improve...

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Detalles Bibliográficos
Autores principales: Anandi, Prathima, Dickson, Alyson L., Feng, QiPing, Wei, Wei-Qi, Dupont, William D., Plummer, Dale, Liu, Ge, Octaria, Rany, Barker, Katherine A., Kawai, Vivian K., Birdwell, Kelly, Cox, Nancy J., Hung, Adriana, Stein, C. Michael, Chung, Cecilia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426242/
https://www.ncbi.nlm.nih.gov/pubmed/32054992
http://dx.doi.org/10.1038/s41397-020-0163-4

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