Cargando…

Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt

BACKGROUND: Regional level data on hospitalized heart failure (HHF) patients in Egypt is scarce. The aim of this study was to compare the demographics, clinical characteristics, and outcomes of HHF patients from four distinct geographical regions of Egypt. RESULTS: Study participants were part of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Hassanin, Ahmed, Hassanein, Mahmoud, Bendary, Ahmed, Maksoud, Madiha Abdel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426340/
https://www.ncbi.nlm.nih.gov/pubmed/32789717
http://dx.doi.org/10.1186/s43044-020-00082-0
_version_ 1783570660844371968
author Hassanin, Ahmed
Hassanein, Mahmoud
Bendary, Ahmed
Maksoud, Madiha Abdel
author_facet Hassanin, Ahmed
Hassanein, Mahmoud
Bendary, Ahmed
Maksoud, Madiha Abdel
author_sort Hassanin, Ahmed
collection PubMed
description BACKGROUND: Regional level data on hospitalized heart failure (HHF) patients in Egypt is scarce. The aim of this study was to compare the demographics, clinical characteristics, and outcomes of HHF patients from four distinct geographical regions of Egypt. RESULTS: Study participants were part of the European Society of Cardiology Heart Failure Long Term (ESC-HF-LT) Registry, which enrolled patients from April 2011 to February 2014. A total of 1661 HHF patients from Egypt were enrolled, of whom 1645 were eligible for analysis: 914 from Alexandria, 249 from Cairo, 409 from the Delta region, and 73 from Upper Egypt. The mean age ranged from 52.2 to 62.8 years and differed significantly between the 4 groups (P < 0.01). Females represented one-third of the cohort (P = 0.5 between groups). The prevalence of obesity, diabetes, and hypertension also varied significantly across the groups (P < 0.01). The most common etiology of heart failure (HF) was ischemic heart disease. HF with reduced systolic function was the leading type of HF in the 4 groups (P = 0.6). The most common valvular abnormality in all regions was mitral regurgitation. For patients with prior history of HF, community-acquired infection was the most common reason for a HF exacerbation in all 4 groups. In-hospital mortality ranged from 2.9 to 7.7% in the 4 groups (P = 0.06). Only Alexandria and Delta groups provided reliable 1-year follow-up data, given low patient retention in Cairo and Upper Egypt groups. At one-year, 32% of patients from Alexandria compared to 22.6% from Delta were re-hospitalized for HF (P < 0.01). Mortality at 1 year was also significantly higher in Alexandria compared to Delta, 31.8 vs 13.2% respectively (P < 0.01). CONCLUSIONS: HHF patients from different geographic regions of Egypt differed significantly in their demographics, clinical characteristics, and outcomes. Those differences underscore the importance of region-specific HF prevention and management strategies.
format Online
Article
Text
id pubmed-7426340
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-74263402020-08-24 Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt Hassanin, Ahmed Hassanein, Mahmoud Bendary, Ahmed Maksoud, Madiha Abdel Egypt Heart J Research BACKGROUND: Regional level data on hospitalized heart failure (HHF) patients in Egypt is scarce. The aim of this study was to compare the demographics, clinical characteristics, and outcomes of HHF patients from four distinct geographical regions of Egypt. RESULTS: Study participants were part of the European Society of Cardiology Heart Failure Long Term (ESC-HF-LT) Registry, which enrolled patients from April 2011 to February 2014. A total of 1661 HHF patients from Egypt were enrolled, of whom 1645 were eligible for analysis: 914 from Alexandria, 249 from Cairo, 409 from the Delta region, and 73 from Upper Egypt. The mean age ranged from 52.2 to 62.8 years and differed significantly between the 4 groups (P < 0.01). Females represented one-third of the cohort (P = 0.5 between groups). The prevalence of obesity, diabetes, and hypertension also varied significantly across the groups (P < 0.01). The most common etiology of heart failure (HF) was ischemic heart disease. HF with reduced systolic function was the leading type of HF in the 4 groups (P = 0.6). The most common valvular abnormality in all regions was mitral regurgitation. For patients with prior history of HF, community-acquired infection was the most common reason for a HF exacerbation in all 4 groups. In-hospital mortality ranged from 2.9 to 7.7% in the 4 groups (P = 0.06). Only Alexandria and Delta groups provided reliable 1-year follow-up data, given low patient retention in Cairo and Upper Egypt groups. At one-year, 32% of patients from Alexandria compared to 22.6% from Delta were re-hospitalized for HF (P < 0.01). Mortality at 1 year was also significantly higher in Alexandria compared to Delta, 31.8 vs 13.2% respectively (P < 0.01). CONCLUSIONS: HHF patients from different geographic regions of Egypt differed significantly in their demographics, clinical characteristics, and outcomes. Those differences underscore the importance of region-specific HF prevention and management strategies. Springer Berlin Heidelberg 2020-08-13 /pmc/articles/PMC7426340/ /pubmed/32789717 http://dx.doi.org/10.1186/s43044-020-00082-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research
Hassanin, Ahmed
Hassanein, Mahmoud
Bendary, Ahmed
Maksoud, Madiha Abdel
Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt
title Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt
title_full Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt
title_fullStr Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt
title_full_unstemmed Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt
title_short Demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of Egypt
title_sort demographics, clinical characteristics, and outcomes among hospitalized heart failure patients across different regions of egypt
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426340/
https://www.ncbi.nlm.nih.gov/pubmed/32789717
http://dx.doi.org/10.1186/s43044-020-00082-0
work_keys_str_mv AT hassaninahmed demographicsclinicalcharacteristicsandoutcomesamonghospitalizedheartfailurepatientsacrossdifferentregionsofegypt
AT hassaneinmahmoud demographicsclinicalcharacteristicsandoutcomesamonghospitalizedheartfailurepatientsacrossdifferentregionsofegypt
AT bendaryahmed demographicsclinicalcharacteristicsandoutcomesamonghospitalizedheartfailurepatientsacrossdifferentregionsofegypt
AT maksoudmadihaabdel demographicsclinicalcharacteristicsandoutcomesamonghospitalizedheartfailurepatientsacrossdifferentregionsofegypt