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Genomic characterization reveals novel mechanisms underlying the valosin-containing protein-mediated cardiac protection against heart failure

Chronic hypertension is a key risk factor for heart failure. However, the underlying molecular mechanisms are not fully understood. Our previous studies found that the valosin-containing protein (VCP), an ATPase-associated protein, was significantly decreased in the hypertensive heart tissues. In th...

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Detalles Bibliográficos
Autores principales: Zhou, Ning, Chen, Xin, Xi, Jing, Ma, Ben, Leimena, Christiana, Stoll, Shaunrick, Qin, Gangjian, Wang, Charles, Qiu, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426568/
https://www.ncbi.nlm.nih.gov/pubmed/32795937
http://dx.doi.org/10.1016/j.redox.2020.101662