Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System

Fusobacterium nucleatum is a common oral bacterium that is enriched in colorectal adenomas and adenocarcinomas (CRC). In humans, high fusobacterial CRC abundance is associated with chemoresistance and poor prognosis. In animal models, fusobacteria accelerate CRC progression. Targeting F. nucleatum m...

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Detalles Bibliográficos
Autores principales: Abed, Jawad, Maalouf, Naseem, Manson, Abigail L., Earl, Ashlee M., Parhi, Lishay, Emgård, Johanna E. M., Klutstein, Michael, Tayeb, Shay, Almogy, Gideon, Atlan, Karine A., Chaushu, Stella, Israeli, Eran, Mandelboim, Ofer, Garrett, Wendy S., Bachrach, Gilad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426652/
https://www.ncbi.nlm.nih.gov/pubmed/32850497
http://dx.doi.org/10.3389/fcimb.2020.00400

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