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Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes

Glioblastoma (GBM) is one of the most aggressive types of cancer, which begins within the brain. It is the most invasive type of glioma developed from astrocytes. Until today, Temozolomide (TMZ) is the only standard chemotherapy for patients with GBM. Even though chemotherapy extends the survival of...

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Detalles Bibliográficos
Autores principales: Harmouch, Ezeddine, Seitlinger, Joseph, Chaddad, Hassan, Ubeaud-Sequier, Geneviève, Barths, Jochen, Saidu, Sani, Désaubry, Laurent, Grandemange, Stéphanie, Massfelder, Thierry, Fuhrmann, Guy, Fioretti, Florence, Dontenwill, Monique, Benkirane-Jessel, Nadia, Idoux-Gillet, Ysia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426813/
https://www.ncbi.nlm.nih.gov/pubmed/32792639
http://dx.doi.org/10.1038/s41598-020-70820-6