Optogenetic control of protein binding using light-switchable nanobodies

A growing number of optogenetic tools have been developed to reversibly control binding between two engineered protein domains. In contrast, relatively few tools confer light-switchable binding to a generic target protein of interest. Such a capability would offer substantial advantages, enabling ph...

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Detalles Bibliográficos
Autores principales: Gil, Agnieszka A., Carrasco-López, César, Zhu, Liyuan, Zhao, Evan M., Ravindran, Pavithran T., Wilson, Maxwell Z., Goglia, Alexander G., Avalos, José L., Toettcher, Jared E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426870/
https://www.ncbi.nlm.nih.gov/pubmed/32792536
http://dx.doi.org/10.1038/s41467-020-17836-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426870/
https://www.ncbi.nlm.nih.gov/pubmed/32792536
http://dx.doi.org/10.1038/s41467-020-17836-8

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