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Optogenetic control of protein binding using light-switchable nanobodies
A growing number of optogenetic tools have been developed to reversibly control binding between two engineered protein domains. In contrast, relatively few tools confer light-switchable binding to a generic target protein of interest. Such a capability would offer substantial advantages, enabling ph...
Autores principales: | Gil, Agnieszka A., Carrasco-López, César, Zhu, Liyuan, Zhao, Evan M., Ravindran, Pavithran T., Wilson, Maxwell Z., Goglia, Alexander G., Avalos, José L., Toettcher, Jared E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426870/ https://www.ncbi.nlm.nih.gov/pubmed/32792536 http://dx.doi.org/10.1038/s41467-020-17836-8 |
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