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Effect of Adjuvant Paclitaxel and Carboplatin on Survival in Women With Triple-Negative Breast Cancer: A Phase 3 Randomized Clinical Trial

IMPORTANCE: The value of platinum-based adjuvant chemotherapy in patients with triple-negative breast cancer (TNBC) remains controversial, as does whether BRCA1 and BRCA2 (BRCA1/2) germline variants are associated with platinum treatment sensitivity. OBJECTIVE: To compare 6 cycles of paclitaxel plus...

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Detalles Bibliográficos
Autores principales: Yu, Ke-Da, Ye, Fu-Gui, He, Min, Fan, Lei, Ma, Ding, Mo, Miao, Wu, Jiong, Liu, Guang-Yu, Di, Gen-Hong, Zeng, Xiao-Hua, He, Ping-Qing, Wu, Ke-Jin, Hou, Yi-Feng, Wang, Jie, Wang, Cheng, Zhuang, Zhi-Gang, Song, Chuan-Gui, Lin, Xiao-Yan, Toss, Angela, Ricci, Francesco, Shen, Zhen-Zhou, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426881/
https://www.ncbi.nlm.nih.gov/pubmed/32789480
http://dx.doi.org/10.1001/jamaoncol.2020.2965