A novel approach to genetic engineering of T-cell subsets by hematopoietic stem cell infection with a bicistronic lentivirus

Lentiviral modification of hematopoietic stem cells (HSCs) paved the way for in vivo experimentation and therapeutic approaches in patients with genetic disease. A disadvantage of this method is the use of a ubiquitous promoter leads not only to genetic modification of the leukocyte subset of intere...

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Detalles Bibliográficos
Autores principales: Bogert, N. V., Furkel, J., Din, S., Braren, I., Eckstein, V., Müller, J. A., Uhlmann, L., Katus, H. A., Konstandin, M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426960/
https://www.ncbi.nlm.nih.gov/pubmed/32792615
http://dx.doi.org/10.1038/s41598-020-70793-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426960/
https://www.ncbi.nlm.nih.gov/pubmed/32792615
http://dx.doi.org/10.1038/s41598-020-70793-6

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