Cargando…

Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery

BACKGROUND: To increase the size of the druggable proteome, it would be highly desirable to devise efficient methods to translocate designed binding proteins to the cytosol, as they could specifically target flat and hydrophobic protein-protein interfaces. If this could be done in a manner dependent...

Descripción completa

Detalles Bibliográficos
Autores principales: Becker, Lukas, Verdurmen, Wouter P. R., Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427085/
https://www.ncbi.nlm.nih.gov/pubmed/32792013
http://dx.doi.org/10.1186/s12915-020-00827-y