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Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery
BACKGROUND: To increase the size of the druggable proteome, it would be highly desirable to devise efficient methods to translocate designed binding proteins to the cytosol, as they could specifically target flat and hydrophobic protein-protein interfaces. If this could be done in a manner dependent...
Autores principales: | Becker, Lukas, Verdurmen, Wouter P. R., Plückthun, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427085/ https://www.ncbi.nlm.nih.gov/pubmed/32792013 http://dx.doi.org/10.1186/s12915-020-00827-y |
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