K18-hACE2 mice develop respiratory disease resembling severe COVID-19

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SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic. Several animal models have been rapidly developed that recapitulate the asymptomatic to moderate disease spectrum. Now, there is a direct need for additional small animal models to study the pathogenesis of severe COVID-1...

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Detalles Bibliográficos
Autores principales: Yinda, Claude Kwe, Port, Julia R., Bushmaker, Trenton, Owusu, Irene Offei, Avanzato, Victoria A., Fischer, Robert J., Schulz, Jonathan E., Holbrook, Myndi G., Hebner, Madison J., Rosenke, Rebecca, Thomas, Tina, Marzi, Andrea, Best, Sonja M., de Wit, Emmie, Shaia, Carl, van Doremalen, Neeltje, Munster, Vincent J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427137/
https://www.ncbi.nlm.nih.gov/pubmed/32803199
http://dx.doi.org/10.1101/2020.08.11.246314
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