Lipid-specific IgMs induce antiviral responses in the CNS: implications for progressive multifocal leukoencephalopathy in multiple sclerosis

Progressive multi-focal leukoencephalopathy (PML) is a potentially fatal encephalitis caused by JC polyomavirus (JCV). PML principally affects people with a compromised immune system, such as patients with multiple sclerosis (MS) receiving treatment with natalizumab. However, intrathecal synthesis o...

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Detalles Bibliográficos
Autores principales: Hayden, Lorna, Semenoff, Tiia, Schultz, Verena, Merz, Simon F., Chapple, Katie J., Rodriguez, Moses, Warrington, Arthur E., Shi, Xiaohong, McKimmie, Clive S., Edgar, Julia M., Thümmler, Katja, Linington, Chris, Pingen, Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427287/
https://www.ncbi.nlm.nih.gov/pubmed/32792006
http://dx.doi.org/10.1186/s40478-020-01011-7

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