ETV4 promotes late development of prostatic intraepithelial neoplasia and cell proliferation through direct and p53-mediated downregulation of p21

BACKGROUND: ETV4 is one of the ETS proteins overexpressed in prostate cancer (PC) as a result of recurrent chromosomal translocations. In human prostate cell lines, ETV4 promotes migration, invasion, and proliferation; however, its role in PC has been unclear. In this study, we have explored the eff...

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Detalles Bibliográficos
Autores principales: Cosi, Irene, Pellecchia, Annamaria, De Lorenzo, Emanuele, Torre, Eugenio, Sica, Michela, Nesi, Gabriella, Notaro, Rosario, De Angioletti, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427297/
https://www.ncbi.nlm.nih.gov/pubmed/32791988
http://dx.doi.org/10.1186/s13045-020-00943-w

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