Is therapeutic anticoagulation improving renal outcomes in COVID-19?

We present three patients with COVID-19 who developed acute renal failure during hospitalization and were seen to have an improvement in their kidney function after being started on therapeutic anticoagulation with heparin (Target PTT 58–93 seconds) for varying indications (atrial fibrillation, popl...

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Detalles Bibliográficos
Autores principales: Roomi, Sohaib, Ullah, Waqas, Farooq, Soban, Saeed, Rehan, Haq, Shujaul, Ashfaq, Ammar Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427433/
https://www.ncbi.nlm.nih.gov/pubmed/32850085
http://dx.doi.org/10.1080/20009666.2020.1785995
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author Roomi, Sohaib
Ullah, Waqas
Farooq, Soban
Saeed, Rehan
Haq, Shujaul
Ashfaq, Ammar Ali
author_facet Roomi, Sohaib
Ullah, Waqas
Farooq, Soban
Saeed, Rehan
Haq, Shujaul
Ashfaq, Ammar Ali
author_sort Roomi, Sohaib
collection PubMed
description We present three patients with COVID-19 who developed acute renal failure during hospitalization and were seen to have an improvement in their kidney function after being started on therapeutic anticoagulation with heparin (Target PTT 58–93 seconds) for varying indications (atrial fibrillation, popliteal vein thrombosis and a pulmonary embolism). Their kidney functions improved significantly following anticoagulation with a clear temporal relationship between the former and latter. Anticoagulation was held for one patient due to concern of gastrointestinal bleeding and his kidney functions worsened a day after stopping anticoagulation. D-dimer levels also improved with anticoagulation but the trend of other inflammatory markers remained unpredictable.
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spelling pubmed-74274332020-08-25 Is therapeutic anticoagulation improving renal outcomes in COVID-19? Roomi, Sohaib Ullah, Waqas Farooq, Soban Saeed, Rehan Haq, Shujaul Ashfaq, Ammar Ali J Community Hosp Intern Med Perspect Brief Report We present three patients with COVID-19 who developed acute renal failure during hospitalization and were seen to have an improvement in their kidney function after being started on therapeutic anticoagulation with heparin (Target PTT 58–93 seconds) for varying indications (atrial fibrillation, popliteal vein thrombosis and a pulmonary embolism). Their kidney functions improved significantly following anticoagulation with a clear temporal relationship between the former and latter. Anticoagulation was held for one patient due to concern of gastrointestinal bleeding and his kidney functions worsened a day after stopping anticoagulation. D-dimer levels also improved with anticoagulation but the trend of other inflammatory markers remained unpredictable. Taylor & Francis 2020-08-02 /pmc/articles/PMC7427433/ /pubmed/32850085 http://dx.doi.org/10.1080/20009666.2020.1785995 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Roomi, Sohaib
Ullah, Waqas
Farooq, Soban
Saeed, Rehan
Haq, Shujaul
Ashfaq, Ammar Ali
Is therapeutic anticoagulation improving renal outcomes in COVID-19?
title Is therapeutic anticoagulation improving renal outcomes in COVID-19?
title_full Is therapeutic anticoagulation improving renal outcomes in COVID-19?
title_fullStr Is therapeutic anticoagulation improving renal outcomes in COVID-19?
title_full_unstemmed Is therapeutic anticoagulation improving renal outcomes in COVID-19?
title_short Is therapeutic anticoagulation improving renal outcomes in COVID-19?
title_sort is therapeutic anticoagulation improving renal outcomes in covid-19?
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427433/
https://www.ncbi.nlm.nih.gov/pubmed/32850085
http://dx.doi.org/10.1080/20009666.2020.1785995
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