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Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling

Combination therapies that display cancer-killing activities through either coexistent targeting of several cellular factors or more efficient suppression of a specific pathway are generally used in cancer treatment. Sildenafil, a specific phosphodiesterase type 5 (PDE5) inhibitor, has been suggeste...

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Detalles Bibliográficos
Autores principales:	Hsu, Jui-Ling, Leu, Wohn-Jenn, Hsu, Lih-Ching, Ho, Chen-Hsun, Liu, Shih-Ping, Guh, Jih-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427565/ https://www.ncbi.nlm.nih.gov/pubmed/32850387 http://dx.doi.org/10.3389/fonc.2020.01274

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