PDCD10-Deficiency Promotes Malignant Behaviors and Tumor Growth via Triggering EphB4 Kinase Activity in Glioblastoma

We previously reported an angiogenic and tumor-suppressor-like function of programmed cell death 10 (PDCD10) in glioblastoma (GBM). However, the underlying mechanism remains to be elucidated. We hypothesized that loss of PDCD10 activates GBM cells and tumor progression via EphB4. To this end, PDCD10...

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Detalles Bibliográficos
Autores principales: Wan, Xueyan, Saban, Dino Vitali, Kim, Su Na, Weng, Yinlun, Dammann, Philipp, Keyvani, Kathy, Sure, Ulrich, Zhu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427606/
https://www.ncbi.nlm.nih.gov/pubmed/32850441
http://dx.doi.org/10.3389/fonc.2020.01377

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