Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study

One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no cir...

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Autores principales: Fernandes, Sara, Teixeira, Catarina, Falcão, Luis Pedro, Costa, Ana Cortesão, Raimundo, Mário, Silva, Sónia, Cardoso, João, Almeida, Edgar De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427652/
https://www.ncbi.nlm.nih.gov/pubmed/30897193
http://dx.doi.org/10.1590/2175-8239-JBN-2019-0003
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author Fernandes, Sara
Teixeira, Catarina
Falcão, Luis Pedro
Costa, Ana Cortesão
Raimundo, Mário
Silva, Sónia
Cardoso, João
Almeida, Edgar De
author_facet Fernandes, Sara
Teixeira, Catarina
Falcão, Luis Pedro
Costa, Ana Cortesão
Raimundo, Mário
Silva, Sónia
Cardoso, João
Almeida, Edgar De
author_sort Fernandes, Sara
collection PubMed
description One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no circulating ANCAs, and this subgroup has been known as the ANCA-negative pauci-immune CrGN. RPGN can be associated with systemic diseases, but there are only few case reports describing the association with mixed connective tissue disease (MCTD). The authors report a case of ANCA-negative CrGN associated with a MCTD.
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spelling pubmed-74276522020-08-25 Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study Fernandes, Sara Teixeira, Catarina Falcão, Luis Pedro Costa, Ana Cortesão Raimundo, Mário Silva, Sónia Cardoso, João Almeida, Edgar De J Bras Nefrol Case Report One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no circulating ANCAs, and this subgroup has been known as the ANCA-negative pauci-immune CrGN. RPGN can be associated with systemic diseases, but there are only few case reports describing the association with mixed connective tissue disease (MCTD). The authors report a case of ANCA-negative CrGN associated with a MCTD. Sociedade Brasileira de Nefrologia 2019-03-18 2020 /pmc/articles/PMC7427652/ /pubmed/30897193 http://dx.doi.org/10.1590/2175-8239-JBN-2019-0003 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fernandes, Sara
Teixeira, Catarina
Falcão, Luis Pedro
Costa, Ana Cortesão
Raimundo, Mário
Silva, Sónia
Cardoso, João
Almeida, Edgar De
Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
title Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
title_full Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
title_fullStr Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
title_full_unstemmed Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
title_short Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
title_sort anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427652/
https://www.ncbi.nlm.nih.gov/pubmed/30897193
http://dx.doi.org/10.1590/2175-8239-JBN-2019-0003
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