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TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1
BACKGROUND: Chemoresistance is emerging as a major barrier to successful treatment in acute myeloid leukemia (AML), and evasion of apoptosis is among the fundamental underlying mechanisms. Therefore, unraveling molecular networks that drive this process constitutes an urgent unmet need. Herein, we a...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427779/ https://www.ncbi.nlm.nih.gov/pubmed/32795319 http://dx.doi.org/10.1186/s13046-020-01658-z |