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TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1

BACKGROUND: Chemoresistance is emerging as a major barrier to successful treatment in acute myeloid leukemia (AML), and evasion of apoptosis is among the fundamental underlying mechanisms. Therefore, unraveling molecular networks that drive this process constitutes an urgent unmet need. Herein, we a...

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Detalles Bibliográficos
Autores principales: Pang, Yihua, Zhao, Yanan, Wang, Yan, Wang, Xinlu, Wang, Ruiqing, Liu, Na, Li, Peng, Ji, Min, Ye, Jingjing, Sun, Tao, Li, Jingxin, Ma, Daoxin, Lu, Fei, Ji, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427779/
https://www.ncbi.nlm.nih.gov/pubmed/32795319
http://dx.doi.org/10.1186/s13046-020-01658-z

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