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Influence of ligand’s directional configuration, chrysenes as model compounds, on the binding activity with aryl hydrocarbon receptor
Understanding what and how physico-chemical factors of a ligand configure conditions for ligand-receptor binding is a key to accurate assessment of toxic potencies of environmental pollutants. We investigated influences of the dipole-driven orientation and resulting directional configuration of liga...
Autores principales: | Kim, Taewoo, Zhen, Juyuan, Lee, Junghyun, Bauer, Robert, Lee, Changkeun, Kwon, Bong-Oh, Chae, Keun Hwa, Hong, Seongjin, Giesy, John P., Chang, Gap Soo, Khim, Jong Seong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428016/ https://www.ncbi.nlm.nih.gov/pubmed/32796895 http://dx.doi.org/10.1038/s41598-020-70704-9 |
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