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Influence of ligand’s directional configuration, chrysenes as model compounds, on the binding activity with aryl hydrocarbon receptor

Understanding what and how physico-chemical factors of a ligand configure conditions for ligand-receptor binding is a key to accurate assessment of toxic potencies of environmental pollutants. We investigated influences of the dipole-driven orientation and resulting directional configuration of liga...

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Detalles Bibliográficos
Autores principales: Kim, Taewoo, Zhen, Juyuan, Lee, Junghyun, Bauer, Robert, Lee, Changkeun, Kwon, Bong-Oh, Chae, Keun Hwa, Hong, Seongjin, Giesy, John P., Chang, Gap Soo, Khim, Jong Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428016/
https://www.ncbi.nlm.nih.gov/pubmed/32796895
http://dx.doi.org/10.1038/s41598-020-70704-9

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