A novel mouse model of chronic suppurative otitis media and its use in preclinical antibiotic evaluation

Chronic suppurative otitis media (CSOM) is a neglected pediatric disease affecting 330 million worldwide for which no new drugs have been introduced for over a decade. We developed a mouse model with utility in preclinical drug evaluation and antimicrobial discovery. Our model used immune-competent...

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Detalles Bibliográficos
Autores principales: Khomtchouk, Kelly M., Kouhi, Ali, Xia, Anping, Bekale, Laurent Adonis, Massa, Solange M., Sweere, Jolien M., Pletzer, Daniel, Hancock, Robert E., Bollyky, Paul L., Santa Maria, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428333/
https://www.ncbi.nlm.nih.gov/pubmed/32851190
http://dx.doi.org/10.1126/sciadv.abc1828

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