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Conformational dynamics of a G protein–coupled receptor helix 8 in lipid membranes

G protein–coupled receptors (GPCRs) are the largest and pharmaceutically most important class of membrane proteins encoded in the human genome, characterized by a seven-transmembrane helix architecture and a C-terminal amphipathic helix 8 (H8). In a minority of GPCR structures solved to date, H8 eit...

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Detalles Bibliográficos
Autores principales:	Dijkman, Patricia M., Muñoz-García, Juan C., Lavington, Steven R., Kumagai, Patricia Suemy, dos Reis, Rosana I., Yin, Daniel, Stansfeld, Phillip J., Costa-Filho, Antonio José, Watts, Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428336/ https://www.ncbi.nlm.nih.gov/pubmed/32851152 http://dx.doi.org/10.1126/sciadv.aav8207

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