Cargando…
Neuro‐Sjögren: Uncommon or underestimated problem?
OBJECTIVES: Sjögren's syndrome (SS) is a chronic inflammatory disease with an autoimmune background with possible complications from peripheral (PNS) and central nervous system (CNS). The aim of this study was to assess the prevalence and to describe the phenotype of peripheral neuropathies in...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428478/ https://www.ncbi.nlm.nih.gov/pubmed/32583978 http://dx.doi.org/10.1002/brb3.1665 |
_version_ | 1783571081433448448 |
---|---|
author | Jaskólska, Marta Chylińska, Magdalena Masiak, Anna Siemiński, Mariusz Ziętkiewicz, Marcin Czuszyńska, Zenobia Smoleńska, Żaneta Zdrojewski, Zbigniew |
author_facet | Jaskólska, Marta Chylińska, Magdalena Masiak, Anna Siemiński, Mariusz Ziętkiewicz, Marcin Czuszyńska, Zenobia Smoleńska, Żaneta Zdrojewski, Zbigniew |
author_sort | Jaskólska, Marta |
collection | PubMed |
description | OBJECTIVES: Sjögren's syndrome (SS) is a chronic inflammatory disease with an autoimmune background with possible complications from peripheral (PNS) and central nervous system (CNS). The aim of this study was to assess the prevalence and to describe the phenotype of peripheral neuropathies in patients with SS. MATERIALS & METHODS: We studied fifty patients with primary Sjögren's syndrome for peripheral nervous system involvement. All patients underwent neurological and rheumatological examination followed by nerve conduction studies (NCS) of nine peripheral nerves. RESULTS: Thirty‐six patients (72%) fulfilled the criteria for the diagnosis of neuropathy. Carpal tunnel syndrome (54%) and axonal sensorimotor neuropathy (22%) were the most common. Neurological symptoms preceded the diagnosis of SS in eight patients. CONCLUSIONS: Peripheral neuropathies are frequent in SS patients. Neurologists should be aware of possible autoimmune causes of neuropathies because clinical manifestations of neuropathy may precede the development of other symptoms of the autoimmune disease. |
format | Online Article Text |
id | pubmed-7428478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74284782020-08-17 Neuro‐Sjögren: Uncommon or underestimated problem? Jaskólska, Marta Chylińska, Magdalena Masiak, Anna Siemiński, Mariusz Ziętkiewicz, Marcin Czuszyńska, Zenobia Smoleńska, Żaneta Zdrojewski, Zbigniew Brain Behav Original Research OBJECTIVES: Sjögren's syndrome (SS) is a chronic inflammatory disease with an autoimmune background with possible complications from peripheral (PNS) and central nervous system (CNS). The aim of this study was to assess the prevalence and to describe the phenotype of peripheral neuropathies in patients with SS. MATERIALS & METHODS: We studied fifty patients with primary Sjögren's syndrome for peripheral nervous system involvement. All patients underwent neurological and rheumatological examination followed by nerve conduction studies (NCS) of nine peripheral nerves. RESULTS: Thirty‐six patients (72%) fulfilled the criteria for the diagnosis of neuropathy. Carpal tunnel syndrome (54%) and axonal sensorimotor neuropathy (22%) were the most common. Neurological symptoms preceded the diagnosis of SS in eight patients. CONCLUSIONS: Peripheral neuropathies are frequent in SS patients. Neurologists should be aware of possible autoimmune causes of neuropathies because clinical manifestations of neuropathy may precede the development of other symptoms of the autoimmune disease. John Wiley and Sons Inc. 2020-06-25 /pmc/articles/PMC7428478/ /pubmed/32583978 http://dx.doi.org/10.1002/brb3.1665 Text en © 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Jaskólska, Marta Chylińska, Magdalena Masiak, Anna Siemiński, Mariusz Ziętkiewicz, Marcin Czuszyńska, Zenobia Smoleńska, Żaneta Zdrojewski, Zbigniew Neuro‐Sjögren: Uncommon or underestimated problem? |
title | Neuro‐Sjögren: Uncommon or underestimated problem? |
title_full | Neuro‐Sjögren: Uncommon or underestimated problem? |
title_fullStr | Neuro‐Sjögren: Uncommon or underestimated problem? |
title_full_unstemmed | Neuro‐Sjögren: Uncommon or underestimated problem? |
title_short | Neuro‐Sjögren: Uncommon or underestimated problem? |
title_sort | neuro‐sjögren: uncommon or underestimated problem? |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428478/ https://www.ncbi.nlm.nih.gov/pubmed/32583978 http://dx.doi.org/10.1002/brb3.1665 |
work_keys_str_mv | AT jaskolskamarta neurosjogrenuncommonorunderestimatedproblem AT chylinskamagdalena neurosjogrenuncommonorunderestimatedproblem AT masiakanna neurosjogrenuncommonorunderestimatedproblem AT sieminskimariusz neurosjogrenuncommonorunderestimatedproblem AT zietkiewiczmarcin neurosjogrenuncommonorunderestimatedproblem AT czuszynskazenobia neurosjogrenuncommonorunderestimatedproblem AT smolenskazaneta neurosjogrenuncommonorunderestimatedproblem AT zdrojewskizbigniew neurosjogrenuncommonorunderestimatedproblem |