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Improving timely treatment with a stroke emergency map: The case of northern China
OBJECTIVE: The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminogen activator (rt‐PA) thrombolysis. However, data on the time delay following the implement...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428498/ https://www.ncbi.nlm.nih.gov/pubmed/32652889 http://dx.doi.org/10.1002/brb3.1743 |
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author | Zhang, Tianli Zhang, Xiaodong Sun, Huisheng Zhou, Feng Lin, Shiqin Sang, Hui Zheng, Nannan Zhao, Ziyi Shi, Jing Li, Weirong |
author_facet | Zhang, Tianli Zhang, Xiaodong Sun, Huisheng Zhou, Feng Lin, Shiqin Sang, Hui Zheng, Nannan Zhao, Ziyi Shi, Jing Li, Weirong |
author_sort | Zhang, Tianli |
collection | PubMed |
description | OBJECTIVE: The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminogen activator (rt‐PA) thrombolysis. However, data on the time delay following the implementation of an SEM in China are limited. METHODS: Data for suspected stroke patients from the SEM registry center of Taiyuan, Shanxi Province, from August 2017 to July 2019, patients’ characteristics, thrombolysis rate, and functional outcome at 90 days were analyzed. RESULTS: One thousand seven hundred and eighty six patients who arrived at hospitals within 4.5 hr of onset were included; 35.9% arrived by emergency medical services (EMSs), and 1,207 (67.6%) of the population received intravenous rt‐PA. As a result of the SEM, the number of patients treated with rt‐PA increased from 63.9% in phase 1 (August 2017 to July 2018) to 70.5% in phase 2 (August 2018 to July 2019). The median onset‐to‐door and onset‐to‐needle times decreased by five minutes (100 [IQR: 62–135] vs. 105 [IQR: 70–145], p = .005) and nine minutes (158 [IQR: 124–197] vs. 167 [IQR: 132–214], p = .001), respectively. Patients in phase 2 achieved greater independent function outcome at 90 days (79.9% vs. 72.1%; adjusted odds ratio, 2.010; 95% confidence interval, 1.444–2.798). The binary logistic regression models revealed that shorter onset‐to‐needle time (OR: 0.994; 95% CI: 0.992–0.997; p < .001) and lower baseline NIHSS scores (OR: 39.120; 95% CI: 23.477–65.188; p < .001 and OR: 18.324; 95% CI: 11.425–29.388; p < .001 and OR: 3.123; 95% CI: 2.044–4.773; p < .001) were significant predictors for the independent function outcome. CONCLUSION: The implementation of a stroke emergency map is more likely to reduce prehospital delays and improve function outcomes. Future efforts should attempt to increase EMS usage. |
format | Online Article Text |
id | pubmed-7428498 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74284982020-08-17 Improving timely treatment with a stroke emergency map: The case of northern China Zhang, Tianli Zhang, Xiaodong Sun, Huisheng Zhou, Feng Lin, Shiqin Sang, Hui Zheng, Nannan Zhao, Ziyi Shi, Jing Li, Weirong Brain Behav Original Research OBJECTIVE: The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminogen activator (rt‐PA) thrombolysis. However, data on the time delay following the implementation of an SEM in China are limited. METHODS: Data for suspected stroke patients from the SEM registry center of Taiyuan, Shanxi Province, from August 2017 to July 2019, patients’ characteristics, thrombolysis rate, and functional outcome at 90 days were analyzed. RESULTS: One thousand seven hundred and eighty six patients who arrived at hospitals within 4.5 hr of onset were included; 35.9% arrived by emergency medical services (EMSs), and 1,207 (67.6%) of the population received intravenous rt‐PA. As a result of the SEM, the number of patients treated with rt‐PA increased from 63.9% in phase 1 (August 2017 to July 2018) to 70.5% in phase 2 (August 2018 to July 2019). The median onset‐to‐door and onset‐to‐needle times decreased by five minutes (100 [IQR: 62–135] vs. 105 [IQR: 70–145], p = .005) and nine minutes (158 [IQR: 124–197] vs. 167 [IQR: 132–214], p = .001), respectively. Patients in phase 2 achieved greater independent function outcome at 90 days (79.9% vs. 72.1%; adjusted odds ratio, 2.010; 95% confidence interval, 1.444–2.798). The binary logistic regression models revealed that shorter onset‐to‐needle time (OR: 0.994; 95% CI: 0.992–0.997; p < .001) and lower baseline NIHSS scores (OR: 39.120; 95% CI: 23.477–65.188; p < .001 and OR: 18.324; 95% CI: 11.425–29.388; p < .001 and OR: 3.123; 95% CI: 2.044–4.773; p < .001) were significant predictors for the independent function outcome. CONCLUSION: The implementation of a stroke emergency map is more likely to reduce prehospital delays and improve function outcomes. Future efforts should attempt to increase EMS usage. John Wiley and Sons Inc. 2020-07-11 /pmc/articles/PMC7428498/ /pubmed/32652889 http://dx.doi.org/10.1002/brb3.1743 Text en © 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Zhang, Tianli Zhang, Xiaodong Sun, Huisheng Zhou, Feng Lin, Shiqin Sang, Hui Zheng, Nannan Zhao, Ziyi Shi, Jing Li, Weirong Improving timely treatment with a stroke emergency map: The case of northern China |
title | Improving timely treatment with a stroke emergency map: The case of northern China |
title_full | Improving timely treatment with a stroke emergency map: The case of northern China |
title_fullStr | Improving timely treatment with a stroke emergency map: The case of northern China |
title_full_unstemmed | Improving timely treatment with a stroke emergency map: The case of northern China |
title_short | Improving timely treatment with a stroke emergency map: The case of northern China |
title_sort | improving timely treatment with a stroke emergency map: the case of northern china |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428498/ https://www.ncbi.nlm.nih.gov/pubmed/32652889 http://dx.doi.org/10.1002/brb3.1743 |
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