Cargando…

Improving timely treatment with a stroke emergency map: The case of northern China

OBJECTIVE: The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminogen activator (rt‐PA) thrombolysis. However, data on the time delay following the implement...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Tianli, Zhang, Xiaodong, Sun, Huisheng, Zhou, Feng, Lin, Shiqin, Sang, Hui, Zheng, Nannan, Zhao, Ziyi, Shi, Jing, Li, Weirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428498/
https://www.ncbi.nlm.nih.gov/pubmed/32652889
http://dx.doi.org/10.1002/brb3.1743
_version_ 1783571086124777472
author Zhang, Tianli
Zhang, Xiaodong
Sun, Huisheng
Zhou, Feng
Lin, Shiqin
Sang, Hui
Zheng, Nannan
Zhao, Ziyi
Shi, Jing
Li, Weirong
author_facet Zhang, Tianli
Zhang, Xiaodong
Sun, Huisheng
Zhou, Feng
Lin, Shiqin
Sang, Hui
Zheng, Nannan
Zhao, Ziyi
Shi, Jing
Li, Weirong
author_sort Zhang, Tianli
collection PubMed
description OBJECTIVE: The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminogen activator (rt‐PA) thrombolysis. However, data on the time delay following the implementation of an SEM in China are limited. METHODS: Data for suspected stroke patients from the SEM registry center of Taiyuan, Shanxi Province, from August 2017 to July 2019, patients’ characteristics, thrombolysis rate, and functional outcome at 90 days were analyzed. RESULTS: One thousand seven hundred and eighty six patients who arrived at hospitals within 4.5 hr of onset were included; 35.9% arrived by emergency medical services (EMSs), and 1,207 (67.6%) of the population received intravenous rt‐PA. As a result of the SEM, the number of patients treated with rt‐PA increased from 63.9% in phase 1 (August 2017 to July 2018) to 70.5% in phase 2 (August 2018 to July 2019). The median onset‐to‐door and onset‐to‐needle times decreased by five minutes (100 [IQR: 62–135] vs. 105 [IQR: 70–145], p = .005) and nine minutes (158 [IQR: 124–197] vs. 167 [IQR: 132–214], p = .001), respectively. Patients in phase 2 achieved greater independent function outcome at 90 days (79.9% vs. 72.1%; adjusted odds ratio, 2.010; 95% confidence interval, 1.444–2.798). The binary logistic regression models revealed that shorter onset‐to‐needle time (OR: 0.994; 95% CI: 0.992–0.997; p < .001) and lower baseline NIHSS scores (OR: 39.120; 95% CI: 23.477–65.188; p < .001 and OR: 18.324; 95% CI: 11.425–29.388; p < .001 and OR: 3.123; 95% CI: 2.044–4.773; p < .001) were significant predictors for the independent function outcome. CONCLUSION: The implementation of a stroke emergency map is more likely to reduce prehospital delays and improve function outcomes. Future efforts should attempt to increase EMS usage.
format Online
Article
Text
id pubmed-7428498
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-74284982020-08-17 Improving timely treatment with a stroke emergency map: The case of northern China Zhang, Tianli Zhang, Xiaodong Sun, Huisheng Zhou, Feng Lin, Shiqin Sang, Hui Zheng, Nannan Zhao, Ziyi Shi, Jing Li, Weirong Brain Behav Original Research OBJECTIVE: The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminogen activator (rt‐PA) thrombolysis. However, data on the time delay following the implementation of an SEM in China are limited. METHODS: Data for suspected stroke patients from the SEM registry center of Taiyuan, Shanxi Province, from August 2017 to July 2019, patients’ characteristics, thrombolysis rate, and functional outcome at 90 days were analyzed. RESULTS: One thousand seven hundred and eighty six patients who arrived at hospitals within 4.5 hr of onset were included; 35.9% arrived by emergency medical services (EMSs), and 1,207 (67.6%) of the population received intravenous rt‐PA. As a result of the SEM, the number of patients treated with rt‐PA increased from 63.9% in phase 1 (August 2017 to July 2018) to 70.5% in phase 2 (August 2018 to July 2019). The median onset‐to‐door and onset‐to‐needle times decreased by five minutes (100 [IQR: 62–135] vs. 105 [IQR: 70–145], p = .005) and nine minutes (158 [IQR: 124–197] vs. 167 [IQR: 132–214], p = .001), respectively. Patients in phase 2 achieved greater independent function outcome at 90 days (79.9% vs. 72.1%; adjusted odds ratio, 2.010; 95% confidence interval, 1.444–2.798). The binary logistic regression models revealed that shorter onset‐to‐needle time (OR: 0.994; 95% CI: 0.992–0.997; p < .001) and lower baseline NIHSS scores (OR: 39.120; 95% CI: 23.477–65.188; p < .001 and OR: 18.324; 95% CI: 11.425–29.388; p < .001 and OR: 3.123; 95% CI: 2.044–4.773; p < .001) were significant predictors for the independent function outcome. CONCLUSION: The implementation of a stroke emergency map is more likely to reduce prehospital delays and improve function outcomes. Future efforts should attempt to increase EMS usage. John Wiley and Sons Inc. 2020-07-11 /pmc/articles/PMC7428498/ /pubmed/32652889 http://dx.doi.org/10.1002/brb3.1743 Text en © 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Zhang, Tianli
Zhang, Xiaodong
Sun, Huisheng
Zhou, Feng
Lin, Shiqin
Sang, Hui
Zheng, Nannan
Zhao, Ziyi
Shi, Jing
Li, Weirong
Improving timely treatment with a stroke emergency map: The case of northern China
title Improving timely treatment with a stroke emergency map: The case of northern China
title_full Improving timely treatment with a stroke emergency map: The case of northern China
title_fullStr Improving timely treatment with a stroke emergency map: The case of northern China
title_full_unstemmed Improving timely treatment with a stroke emergency map: The case of northern China
title_short Improving timely treatment with a stroke emergency map: The case of northern China
title_sort improving timely treatment with a stroke emergency map: the case of northern china
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428498/
https://www.ncbi.nlm.nih.gov/pubmed/32652889
http://dx.doi.org/10.1002/brb3.1743
work_keys_str_mv AT zhangtianli improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT zhangxiaodong improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT sunhuisheng improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT zhoufeng improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT linshiqin improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT sanghui improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT zhengnannan improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT zhaoziyi improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT shijing improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina
AT liweirong improvingtimelytreatmentwithastrokeemergencymapthecaseofnorthernchina